2f2i: Difference between revisions

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==Solution structure of [P20D,V21K]-kalata B1==
==Solution structure of [P20D,V21K]-kalata B1==
<StructureSection load='2f2i' size='340' side='right'caption='[[2f2i]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2f2i' size='340' side='right'caption='[[2f2i]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2f2i]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F2I FirstGlance]. <br>
<table><tr><td colspan='2'>[[2f2i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oldenlandia_affinis Oldenlandia affinis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F2I FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2f2j|2f2j]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2i OCA], [https://pdbe.org/2f2i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f2i RCSB], [https://www.ebi.ac.uk/pdbsum/2f2i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f2i ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f2i OCA], [https://pdbe.org/2f2i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f2i RCSB], [https://www.ebi.ac.uk/pdbsum/2f2i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f2i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/KAB1_OLDAF KAB1_OLDAF]] Probably participates in a plant defense mechanism. Has antibiotic activity. Has a diuretic effect. Has a uterotonic effect in humans. Active against the Gram-positive S.aureus with a minimum inhibition concentration of approximately 0.2 microM. Relatively ineffective against Gram-negative bacteria such as E.coli and P.aeruginosa. Inhibitory effect on the growth and development of larvae from H.punctigera. The unmodified form has hemolytic activity, the oxidized form lacks hemolytic activity. If the protein is linearized, hemolytic activity is lost.<ref>PMID:17534989</ref> <ref>PMID:12779323</ref>
[https://www.uniprot.org/uniprot/KAB1_OLDAF KAB1_OLDAF] Probably participates in a plant defense mechanism. Has antibiotic activity. Has a diuretic effect. Has a uterotonic effect in humans. Active against the Gram-positive S.aureus with a minimum inhibition concentration of approximately 0.2 microM. Relatively ineffective against Gram-negative bacteria such as E.coli and P.aeruginosa. Inhibitory effect on the growth and development of larvae from H.punctigera. The unmodified form has hemolytic activity, the oxidized form lacks hemolytic activity. If the protein is linearized, hemolytic activity is lost.<ref>PMID:17534989</ref> <ref>PMID:12779323</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Clark, R J]]
[[Category: Oldenlandia affinis]]
[[Category: Craik, D J]]
[[Category: Clark RJ]]
[[Category: Daly, N L]]
[[Category: Craik DJ]]
[[Category: Antimicrobial protein]]
[[Category: Daly NL]]
[[Category: Beta-hairpin]]
[[Category: Circular backbone]]
[[Category: Cystine knot]]
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