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<StructureSection load='3jtp' size='340' side='right'caption='[[3jtp]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
<StructureSection load='3jtp' size='340' side='right'caption='[[3jtp]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3jtp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JTP FirstGlance]. <br>
<table><tr><td colspan='2'>[[3jtp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JTP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3jtn|3jtn]], [[3jto|3jto]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mecA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jtp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtp OCA], [https://pdbe.org/3jtp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jtp RCSB], [https://www.ebi.ac.uk/pdbsum/3jtp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jtp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jtp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtp OCA], [https://pdbe.org/3jtp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jtp RCSB], [https://www.ebi.ac.uk/pdbsum/3jtp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jtp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/MECA1_BACSU MECA1_BACSU]] Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.<ref>PMID:12598648</ref>
[https://www.uniprot.org/uniprot/MECA1_BACSU MECA1_BACSU] Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.<ref>PMID:12598648</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Vibrio subtilis ehrenberg 1835]]
[[Category: Bacillus subtilis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Mei, Z]]
[[Category: Mei Z]]
[[Category: Qi, Y]]
[[Category: Qi Y]]
[[Category: Shi, Y]]
[[Category: Shi Y]]
[[Category: Wang, F]]
[[Category: Wang F]]
[[Category: Wang, J]]
[[Category: Wang J]]
[[Category: Yan, C]]
[[Category: Yan C]]
[[Category: Adaptor protein]]
[[Category: Competence]]
[[Category: Degradation tag]]
[[Category: Meca]]
[[Category: Protein binding]]
[[Category: Sporulation]]
Retrieved from "https://proteopedia.org/3jtp"