1foo: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
Line 1: Line 1:
[[Image:1foo.gif|left|200px]]
{{Seed}}
[[Image:1foo.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1foo|  PDB=1foo  |  SCENE=  }}  
{{STRUCTURE_1foo|  PDB=1foo  |  SCENE=  }}  


'''BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-ARG AND NO(H4B-FREE)'''
===BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-ARG AND NO(H4B-FREE)===




==Overview==
<!--
The crystal structure of the endothelial nitric oxide synthase (NOS) heme domain complexed with NO reveals close hydrogen bonding interactions between NO and the terminal guanidino nitrogen of the substrate, L-arginine. Dioxygen is expected to bind in a similar mode which will facilitate proton abstraction from L-Arg to dioxygen, a required step for O-O bond cleavage. Structures of mechanism-based NOS inhibitors, N(5)-(1-iminoethyl)-L-ornithine and N-(3-(aminomethyl)benzyl)acetamidine, provide clues on how this class of compounds operate as suicide substrate inhibitors leading to heme oxidation.
The line below this paragraph, {{ABSTRACT_PUBMED_11331003}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11331003 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_11331003}}


==About this Structure==
==About this Structure==
Line 30: Line 34:
[[Category: Alpha-beta fold]]
[[Category: Alpha-beta fold]]
[[Category: Nitric oxide synthase]]
[[Category: Nitric oxide synthase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 16:34:53 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 03:41:34 2008''
Retrieved from "https://proteopedia.org/1foo"