7ny1: Difference between revisions
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==Structure of the fungal plasma membrane proton pump Pma1 in its auto-inhibited state - hexameric assembly== | ==Structure of the fungal plasma membrane proton pump Pma1 in its auto-inhibited state - hexameric assembly== | ||
<StructureSection load='7ny1' size='340' side='right'caption='[[7ny1]]' scene=''> | <StructureSection load='7ny1' size='340' side='right'caption='[[7ny1]], [[Resolution|resolution]] 3.26Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NY1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NY1 FirstGlance]. <br> | <table><tr><td colspan='2'>[[7ny1]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Neurospora_crassa Neurospora crassa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NY1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NY1 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ny1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ny1 OCA], [https://pdbe.org/7ny1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ny1 RCSB], [https://www.ebi.ac.uk/pdbsum/7ny1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ny1 ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7nxf|7nxf]]</div></td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/P-type_H(+)-exporting_transporter P-type H(+)-exporting transporter], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=7.1.2.1 7.1.2.1] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ny1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ny1 OCA], [https://pdbe.org/7ny1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ny1 RCSB], [https://www.ebi.ac.uk/pdbsum/7ny1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ny1 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/A0A0B0DXJ0_NEUCS A0A0B0DXJ0_NEUCS]] The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.[ARBA:ARBA00003417] | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
[Figure: see text]. | |||
Structure of the hexameric fungal plasma membrane proton pump in its autoinhibited state.,Heit S, Geurts MMG, Murphy BJ, Corey RA, Mills DJ, Kuhlbrandt W, Bublitz M Sci Adv. 2021 Nov 12;7(46):eabj5255. doi: 10.1126/sciadv.abj5255. Epub 2021 Nov, 10. PMID:34757782<ref>PMID:34757782</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 7ny1" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bublitz M]] | [[Category: Neurospora crassa]] | ||
[[Category: Corey R]] | [[Category: Bublitz, M]] | ||
[[Category: Geurts | [[Category: Corey, R]] | ||
[[Category: Heit S]] | [[Category: Geurts, M M.G]] | ||
[[Category: Kuehlbrandt W]] | [[Category: Heit, S]] | ||
[[Category: Mills | [[Category: Kuehlbrandt, W]] | ||
[[Category: Murphy | [[Category: Mills, D J]] | ||
[[Category: Murphy, B J]] | |||
[[Category: Membrane protein]] | |||
[[Category: P-type atpase]] | |||
[[Category: Proton transport]] | |||
[[Category: Proton-transporting atpase]] | |||
