7rdb: Difference between revisions

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<StructureSection load='7rdb' size='340' side='right'caption='[[7rdb]], [[Resolution|resolution]] 2.52&Aring;' scene=''>
<StructureSection load='7rdb' size='340' side='right'caption='[[7rdb]], [[Resolution|resolution]] 2.52&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7rdb]] is a 24 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RDB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RDB FirstGlance]. <br>
<table><tr><td colspan='2'>[[7rdb]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RDB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RDB FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7rd5|7rd5]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.52&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rdb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rdb OCA], [https://pdbe.org/7rdb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rdb RCSB], [https://www.ebi.ac.uk/pdbsum/7rdb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rdb ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rdb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rdb OCA], [https://pdbe.org/7rdb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rdb RCSB], [https://www.ebi.ac.uk/pdbsum/7rdb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rdb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/TSN15_HUMAN TSN15_HUMAN]] Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:26686862, PubMed:30463011). Promotes ADAM10-mediated cleavage of CDH2 (By similarity). Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (PubMed:26686862).[UniProtKB:F7BWT7]<ref>PMID:26686862</ref> <ref>PMID:30463011</ref>
[https://www.uniprot.org/uniprot/TSN15_HUMAN TSN15_HUMAN] Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:26686862, PubMed:30463011). Promotes ADAM10-mediated cleavage of CDH2 (By similarity). Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (PubMed:26686862).[UniProtKB:F7BWT7]<ref>PMID:26686862</ref> <ref>PMID:30463011</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Blacklow, S C]]
[[Category: Blacklow SC]]
[[Category: Durr, K L]]
[[Category: Durr KL]]
[[Category: Gabriel, K H]]
[[Category: Gabriel KH]]
[[Category: Lipper, C H]]
[[Category: Lipper CH]]
[[Category: Seegar, T C.M]]
[[Category: Seegar TCM]]
[[Category: Tomlinson, M G]]
[[Category: Tomlinson MG]]
[[Category: Cell adhesion]]
[[Category: Membrane protein]]
[[Category: Protein trafficking]]
[[Category: Tetraspanin]]
Retrieved from "https://proteopedia.org/7rdb"