2y71: Difference between revisions

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<StructureSection load='2y71' size='340' side='right'caption='[[2y71]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='2y71' size='340' side='right'caption='[[2y71]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2y71]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y71 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2y71]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y71 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CB6:(1R,4S,5R)-1,4,5-TRIHYDROXY-3-[(5-METHYL-1-BENZOTHIOPHEN-2-YL)METHOXY]CYCLOHEX-2-ENE-1-CARBOXYLIC+ACID'>CB6</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1h0r|1h0r]], [[2xb8|2xb8]], [[1h05|1h05]], [[2dhq|2dhq]], [[1h0s|1h0s]], [[2y76|2y76]], [[2y77|2y77]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CB6:(1R,4S,5R)-1,4,5-TRIHYDROXY-3-[(5-METHYL-1-BENZOTHIOPHEN-2-YL)METHOXY]CYCLOHEX-2-ENE-1-CARBOXYLIC+ACID'>CB6</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y71 OCA], [https://pdbe.org/2y71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y71 RCSB], [https://www.ebi.ac.uk/pdbsum/2y71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y71 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y71 OCA], [https://pdbe.org/2y71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y71 RCSB], [https://www.ebi.ac.uk/pdbsum/2y71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y71 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU]] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]  
[https://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 3-dehydroquinate dehydratase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ainsa, J A]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Castedo, L]]
[[Category: Ainsa JA]]
[[Category: Fox, G C]]
[[Category: Castedo L]]
[[Category: Gonzalez-Bello, C]]
[[Category: Fox GC]]
[[Category: Hawkins, A R]]
[[Category: Gonzalez-Bello C]]
[[Category: Lamb, H]]
[[Category: Hawkins AR]]
[[Category: Llamas-Saiz, A L]]
[[Category: Lamb H]]
[[Category: Otero, J M]]
[[Category: Llamas-Saiz AL]]
[[Category: Prazeres, V F.V]]
[[Category: Otero JM]]
[[Category: Raaij, M J.van]]
[[Category: Prazeres VFV]]
[[Category: Tizon, L]]
[[Category: Tizon L]]
[[Category: Amino acid biosynthesis]]
[[Category: Van Raaij MJ]]
[[Category: Lyase]]