Nitroreductase: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
Michal Harel (talk | contribs)
32,831 edits
No edit summary
Michal Harel (talk | contribs)
32,831 edits
No edit summary
Line 18: Line 18:
*Nitroreductase
*Nitroreductase


**[[1f5v ]], [[1oo5]] – EcNR + FMN – ''Escherichia coli''<br />
**[[3bm1]], [[1ds7]] – EcNR minimal + FMN – ''Escherichia coli''<br />
**[[3x21]], [[3x22]] – EcNR (mutant) + FMN<br />
**[[3bm1]], [[1ds7]] – EcNR minimal + FMN<br />
**[[3bm2]] – EcNR minimal -FMN<br />
**[[3bm2]] – EcNR minimal -FMN<br />
**[[1nec]], [[1kqd]] – EclNR + FMN – ''Enterobacter cloacae''<br />
**[[1nec]], [[1kqd]] – EclNR + FMN – ''Enterobacter cloacae''<br />
**[[1kqb]], [[5j8g]]– EclNR + FMN + benzoate derivative<br />
**[[1kqc]] – EclNR + FMN + acetate<br />
**[[1ywq]], [[2i7h]] – NR + FMN – ''Bacillus cereus''<br />
**[[1ywq]], [[2i7h]] – NR + FMN – ''Bacillus cereus''<br />
**[[5hdj]] – NR + FMN – ''Bacillus megaterium''<br />
**[[5hdj]] – NR + FMN – ''Bacillus megaterium''<br />
Line 33: Line 33:
**[[3k6h]] – NR + FMN – ''Agrobacterium tumefaciens''<br />
**[[3k6h]] – NR + FMN – ''Agrobacterium tumefaciens''<br />
**[[2wzv]], [[2ymv]] – MsNR + FMN – ''Mycobacterium smegmatis''<br />
**[[2wzv]], [[2ymv]] – MsNR + FMN – ''Mycobacterium smegmatis''<br />
**[[2wzw]] - MsNR + FMN + NADPH<br />
**[[3of4]] – NR + FMN + FAD – ''Idiomarina loihiensis''<br />
**[[3of4]] – NR + FMN + FAD – ''Idiomarina loihiensis''<br />
**[[3n2s]] – NR + FMN – ''Bacillus subtilis''<br />
**[[3n2s]] – NR + FMN – ''Bacillus subtilis''<br />
**[[3pxv]] – NR + FMN – ''Desulfitobacterium hafniense''<br />
**[[3pxv]] – NR + FMN – ''Desulfitobacterium hafniense''<br />
**[[3qdl]] – NR + FMN – ''Helicobacter pylori''<br />
**[[3r5l]], [[3r5p]] - MtNR – ''Mycobacterium tuberculosis''<br />
**[[3r5l]], [[3r5p]] - MtNR – ''Mycobacterium tuberculosis''<br />
**[[3ge6]] – NR + FMN – ''Exiguobacterium sibiricum''<br />
**[[3ge6]] – NR + FMN – ''Exiguobacterium sibiricum''<br />
Line 43: Line 43:
**[[7dp0]] – SpNR + FMN – ''Sphingopyxis''<br />
**[[7dp0]] – SpNR + FMN – ''Sphingopyxis''<br />
**[[7dp1]], [[7dp2]] – SpNR (mutant) + FMN <br />
**[[7dp1]], [[7dp2]] – SpNR (mutant) + FMN <br />
**[[6czp]] – NR + FMN – ''Vibrio vulnificus''<br />


*Copper-induced nitroreductase
*Copper-induced nitroreductase
Line 56: Line 55:


**[[4z85]] – NR – ''Psudomonas fluorescens''<br />
**[[4z85]] – NR – ''Psudomonas fluorescens''<br />
*Oxygen-insensitive NADPH nitroreductase


*Nitroreductase complex
**[[1f5v]], [[1oo5]], [[7q0o]] – EcNR + FMN <br />
 
**[[3x21]], [[3x22]] – EcNR (mutant) + FMN<br />
**[[1kqb]], [[5j8g]]– EclNR + FMN + benzoate derivative<br />
**[[7z0w]] – EcNR + FMN + adenosine derivative<br />
**[[1kqc]] – EclNR + FMN + acetate<br />
**[[7xww]] – EcNR + FMN + pyridine derivative<br />
**[[8c5e]], [[8ccv]], [[8cj0]] – EcNR (mutant) + FMN + nicotinic acid<br />
**[[1ylr]], [[1ylu]] - EcNR + FMN + acetate<br />
**[[1ylr]], [[1ylu]] - EcNR + FMN + acetate<br />
**[[8c5f]], [[8c5p]] – EcNR (mutant) + FMN + acetate<br />
**[[8og3]] – EcNR (mutant) + FMN + citrate<br />
**[[7niy]] – EcNR (mutant) + FMN + imidazole<br />
**[[8ajx]] – EcNR + FMN + fumarate<br />
**[[7x32]] – EcNR + FMN + berberine<br />
**[[7nb9]] – EcNR + FMN + nitrofurantoin<br />
**[[7nmp]], [[7nnx]] – EcNR + FMN + quinone derivative<br />
**[[1icr]], [[1icu]], [[1icv]], [[5j8d]] – EcNR + FMN + NAD derivative<br />
**[[1icr]], [[1icu]], [[1icv]], [[5j8d]] – EcNR + FMN + NAD derivative<br />
**[[1ooq]] – EcNR + FMN + dicoumarol<br />
**[[1ooq]] – EcNR + FMN + dicoumarol<br />
**[[1oo6]], [[1oon]], [[1idt]] – EcNR + FMN + benzamide derivative<br />
**[[1oo6]], [[1oon]], [[1idt]] – EcNR + FMN + benzamide derivative<br />
**[[1yki]] – EcNR + FMN + antibiotic<br />
**[[1yki]] – EcNR + FMN + antibiotic<br />
**[[7nb9]] – EcNR + FMN + nitrofurantoin<br />
**[[6czp]] – VvNR + FMN – Vibrio vulnificus<br />
**[[7nmp]], [[7nnx]] – EcNR + FMN + quinone derivative<br />
**[[7uwt]] – VvNR (mutant) + FMN<br />
**[[7niy]] – EcNR (mutant) + FMN + imidazole<br />
**[[3qdl]] – NR + FMN – Helicobacter pylori<br />
**[[2wzw]] - MsNR + FMN + NADPH<br />
 
**[[6czp]] – NR + FMN – ''Vibrio vulnificus''<br />
*Deazaflavin-dependent nitroreductase
**[[3r5r]], [[3r5w]] – MtNR F420<br />
 
**[[3r5r]], [[3r5w]], [[7kl8]] – MtNR + coenzyme F420<br />
 
*NADPH nitroreductase
 
**[[7tmf]], [[7tmg]] – NR + FMN – Klebsiella pneumoniae<br />
 
*NADPH-flavin nitroreductase
 
**[[5uu6]] – NR + FMN – Vibrio parahaemolyticus<br />
 
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:48, 19 July 2023

E. coli nitroreductase dimer containing FMN and nicotinic acid (PDB entry 1icr)

Drag the structure with the mouse to rotate

3D structures of nitroreductase

Updated on 19-July-2023

  • Oxygen-insensitive NADPH nitroreductase
    • 1f5v, 1oo5, 7q0o – EcNR + FMN
    • 3x21, 3x22 – EcNR (mutant) + FMN
    • 7z0w – EcNR + FMN + adenosine derivative
    • 7xww – EcNR + FMN + pyridine derivative
    • 8c5e, 8ccv, 8cj0 – EcNR (mutant) + FMN + nicotinic acid
    • 1ylr, 1ylu - EcNR + FMN + acetate
    • 8c5f, 8c5p – EcNR (mutant) + FMN + acetate
    • 8og3 – EcNR (mutant) + FMN + citrate
    • 7niy – EcNR (mutant) + FMN + imidazole
    • 8ajx – EcNR + FMN + fumarate
    • 7x32 – EcNR + FMN + berberine
    • 7nb9 – EcNR + FMN + nitrofurantoin
    • 7nmp, 7nnx – EcNR + FMN + quinone derivative
    • 1icr, 1icu, 1icv, 5j8d – EcNR + FMN + NAD derivative
    • 1ooq – EcNR + FMN + dicoumarol
    • 1oo6, 1oon, 1idt – EcNR + FMN + benzamide derivative
    • 1yki – EcNR + FMN + antibiotic
    • 6czp – VvNR + FMN – Vibrio vulnificus
    • 7uwt – VvNR (mutant) + FMN
    • 3qdl – NR + FMN – Helicobacter pylori
  • Deazaflavin-dependent nitroreductase
  • NADPH nitroreductase
    • 7tmf, 7tmg – NR + FMN – Klebsiella pneumoniae
  • NADPH-flavin nitroreductase
    • 5uu6 – NR + FMN – Vibrio parahaemolyticus

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "https://proteopedia.org/index.php?title=Nitroreductase&oldid=3808807"