2bmf: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2bmf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_2 Dengue virus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BMF FirstGlance]. <br> | <table><tr><td colspan='2'>[[2bmf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_2 Dengue virus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BMF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BMF FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.41Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bmf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bmf OCA], [https://pdbe.org/2bmf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bmf RCSB], [https://www.ebi.ac.uk/pdbsum/2bmf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bmf ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bmf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bmf OCA], [https://pdbe.org/2bmf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bmf RCSB], [https://www.ebi.ac.uk/pdbsum/2bmf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bmf ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/Q91H74_9FLAV Q91H74_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774] | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Dengue virus 2]] | [[Category: Dengue virus 2]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Chao | [[Category: Chao A]] | ||
[[Category: Chene | [[Category: Chene P]] | ||
[[Category: Lescar | [[Category: Lescar J]] | ||
[[Category: Nanao | [[Category: Nanao M]] | ||
[[Category: Sampath | [[Category: Sampath A]] | ||
[[Category: Vasudevan | [[Category: Vasudevan SG]] | ||
[[Category: Wen | [[Category: Wen D]] | ||
[[Category: Xu | [[Category: Xu T]] | ||
