2yqe: Difference between revisions
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==Solution structure of the ARID domain of JARID1D protein== | ==Solution structure of the ARID domain of JARID1D protein== | ||
<StructureSection load='2yqe' size='340' side='right'caption='[[2yqe | <StructureSection load='2yqe' size='340' side='right'caption='[[2yqe]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2yqe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2yqe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YQE FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqe OCA], [https://pdbe.org/2yqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yqe RCSB], [https://www.ebi.ac.uk/pdbsum/2yqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yqe ProSAT], [https://www.topsan.org/Proteins/RSGI/2yqe TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqe OCA], [https://pdbe.org/2yqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yqe RCSB], [https://www.ebi.ac.uk/pdbsum/2yqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yqe ProSAT], [https://www.topsan.org/Proteins/RSGI/2yqe TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/KDM5D_HUMAN KDM5D_HUMAN] Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis.<ref>PMID:17320160</ref> <ref>PMID:17320162</ref> <ref>PMID:17351630</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Inoue | [[Category: Inoue M]] | ||
[[Category: Kigawa | [[Category: Kigawa T]] | ||
[[Category: Muto | [[Category: Muto Y]] | ||
[[Category: Shirouzu M]] | |||
[[Category: Shirouzu | [[Category: Suzuki S]] | ||
[[Category: Suzuki | [[Category: Tanabe W]] | ||
[[Category: Tanabe | [[Category: Terada T]] | ||
[[Category: Terada | [[Category: Yokoyama S]] | ||
[[Category: Yokoyama | |||
Latest revision as of 19:16, 29 May 2024
Solution structure of the ARID domain of JARID1D protein
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