Enkephalin: Difference between revisions
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Decreased plasma met-enkephalin levels are vasogenic mediators in Systemic Sclerosis (SSc), and will associate with clinical manifestations of SSc-related vascular and fibrogenic injuries<ref>McNearney TA, Sluka KA, Ahn C, Reveille JD, Fischbach M, Mayes MD. Plasma endogenous enkephalin levels in early systemic sclerosis: clinical and laboratory associations. Clin Exp Rheumatol. 2010;28(2 Suppl 58):S7-S11.</ref>. | Decreased plasma met-enkephalin levels are vasogenic mediators in Systemic Sclerosis (SSc), and will associate with clinical manifestations of SSc-related vascular and fibrogenic injuries<ref>McNearney TA, Sluka KA, Ahn C, Reveille JD, Fischbach M, Mayes MD. Plasma endogenous enkephalin levels in early systemic sclerosis: clinical and laboratory associations. Clin Exp Rheumatol. 2010;28(2 Suppl 58):S7-S11.</ref>. | ||
== Clinical relevance == | == Clinical relevance == | ||
Met-Enkephalin (MENK) may contribute to immune responses against tumors and viral infections by activating multiple types of immune cells, enabling them to secrete various cytokines or directly kill target cells. The nuclear membrane of certain cancer cells expressed receptors to which MENK bound, resulting in marked growth inhibition of cancer cells in vitro<ref>Wang DM, Wang GC, Yang J, Plotnikoff NP, Griffin N, Han YM, Qi RQ, Gao XH and Shan FP: Inhibition of the growth of human melanoma cells by methionine enkephalin. Mol Med Rep 14: 5521-5527, 2016</ref>. | |||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
== References == | == References == | ||
<references/> | <references/> | ||
