Transmembrane protease serine 2: Difference between revisions
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TMPRSS2 is a 492 amino acid single-pass type II membrane protein. This protein is defined by the presence of an N-terminal cytoplasmic domain, a transmembrane helical domain, and three extracellular domains: <ref>DOI 10.1136/jclinpath-2020-206987</ref><scene name='89/897681/Domains/2'>TMPRSS2 protein domains</scene> | TMPRSS2 is a 492 amino acid single-pass type II membrane protein. This protein is defined by the presence of an N-terminal cytoplasmic domain, a transmembrane helical domain, and three extracellular domains: <ref>DOI 10.1136/jclinpath-2020-206987</ref><scene name='89/897681/Domains/2'>TMPRSS2 protein domains</scene> | ||
*Low-density lipoprotein (LDL)-receptor class A domain: which forms a binding site for calcium | *Low-density lipoprotein (LDL)-receptor class A domain: which forms a binding site for calcium r | ||
*Scavenger receptor cysteine-rich domain (SRCR) | *Scavenger receptor cysteine-rich domain (SRCR) | ||
*Peptidase S1 domain, also known as serine protease domain (SPD) | *Peptidase S1 domain, also known as serine protease domain (SPD) | ||