2z04: Difference between revisions

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<StructureSection load='2z04' size='340' side='right'caption='[[2z04]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
<StructureSection load='2z04' size='340' side='right'caption='[[2z04]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2z04]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z04 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2z04]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z04 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">purK ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 "Aquifex aeolicus" Huber and Stetter 2001])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z04 OCA], [https://pdbe.org/2z04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z04 RCSB], [https://www.ebi.ac.uk/pdbsum/2z04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z04 ProSAT], [https://www.topsan.org/Proteins/RSGI/2z04 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z04 OCA], [https://pdbe.org/2z04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z04 RCSB], [https://www.ebi.ac.uk/pdbsum/2z04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z04 ProSAT], [https://www.topsan.org/Proteins/RSGI/2z04 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PURK_AQUAE PURK_AQUAE]] Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) (By similarity).  
[https://www.uniprot.org/uniprot/PURK_AQUAE PURK_AQUAE] Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z0/2z04_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z0/2z04_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aquifex aeolicus huber and stetter 2001]]
[[Category: Aquifex aeolicus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Phosphoribosylaminoimidazole carboxylase]]
[[Category: Baba S]]
[[Category: Baba, S]]
[[Category: Kanagawa M]]
[[Category: Kanagawa, M]]
[[Category: Kawai G]]
[[Category: Kawai, G]]
[[Category: Okada K]]
[[Category: Okada, K]]
[[Category: Sampei G]]
[[Category: Structural genomic]]
[[Category: Tamura S]]
[[Category: Sampei, G]]
[[Category: Tamura, S]]
[[Category: Atp-binding]]
[[Category: Decarboxylase]]
[[Category: Lyase]]
[[Category: Metabolic system]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Nucleotide-binding]]
[[Category: Purine biosynthesis]]
[[Category: Purine nucleotide biosynthetic pathway]]
[[Category: Rsgi]]

Latest revision as of 08:40, 30 October 2024

Crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit from Aquifex aeolicus

2z04, resolution 2.35Å

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