7e17: Difference between revisions
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==Structure of dimeric uPAR== | ==Structure of dimeric uPAR== | ||
<StructureSection load='7e17' size='340' side='right'caption='[[7e17]]' scene=''> | <StructureSection load='7e17' size='340' side='right'caption='[[7e17]], [[Resolution|resolution]] 2.96Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7E17 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7E17 FirstGlance]. <br> | <table><tr><td colspan='2'>[[7e17]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7E17 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7E17 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7e17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7e17 OCA], [https://pdbe.org/7e17 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7e17 RCSB], [https://www.ebi.ac.uk/pdbsum/7e17 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7e17 ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7e17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7e17 OCA], [https://pdbe.org/7e17 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7e17 RCSB], [https://www.ebi.ac.uk/pdbsum/7e17 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7e17 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/UPAR_HUMAN UPAR_HUMAN]] Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Cai Y]] | [[Category: Cai, Y]] | ||
[[Category: Huang M]] | [[Category: Huang, M]] | ||
[[Category: Cell invasion]] | |||
[[Category: Gpi-anchored protein]] | |||
