Sandbox Reserved 1091: Difference between revisions
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In the '''kallikrein/kinin system''', the ASP induce the production of kinin from kininogen (low MW or high MW). The kinin also release caused edema at the infection site and shock in the circulation. <ref>Mechanisms of Inflammation and Tissue Repair. Gary S. Firestein, Goldman’s Cecil Medicine (Twenty Fourth Edition) (2012)</ref> | In the '''kallikrein/kinin system''', the ASP induce the production of kinin from kininogen (low MW or high MW). The kinin also release caused edema at the infection site and shock in the circulation. <ref>Mechanisms of Inflammation and Tissue Repair. Gary S. Firestein, Goldman’s Cecil Medicine (Twenty Fourth Edition) (2012)</ref> | ||
Experiments have been done | Experiments have been done to try to reduce the virulence activity of ASP. It has been demonstrated that the [http://fr.wikipedia.org/wiki/Alpha-2_macroglobuline α2-macroglobulin], a plasma protein, can limit ASP activity. This protein can bind to ASP which is thus inactivated. <ref>Inhibition of Aeromonas sobria serine protease (ASP) by α2-macroglobulin. Murakami Y et al. Biol Chem. 393(10):1193-200 (2012)</ref> | ||
