7sx1: Difference between revisions
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==human triosephosphate isomerase mutant v154m== | |||
<StructureSection load='7sx1' size='340' side='right'caption='[[7sx1]], [[Resolution|resolution]] 2.23Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7sx1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SX1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SX1 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sx1 OCA], [https://pdbe.org/7sx1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sx1 RCSB], [https://www.ebi.ac.uk/pdbsum/7sx1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sx1 ProSAT]</span></td></tr> | ||
[[Category: Romero | </table> | ||
== Disease == | |||
[https://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN] Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:[https://omim.org/entry/190450 190450]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Romero JM]] | |||
Revision as of 10:37, 30 November 2022
human triosephosphate isomerase mutant v154m
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