FirstGlance/Visualizing Conservation: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Eric Martz (talk | contribs) |
Eric Martz (talk | contribs) |
||
| Line 237: | Line 237: | ||
FirstGlance automatically detects [[Protein crosslinks|covalent protein crosslinks of six types]], plus disulfide bonds. Tools are provided making it easy to examine each such crosslink in detail. If the PDB file has been processed by [[ConSurf/Index|ConSurf]], it is easy to see the levels of conservation of the crosslinked residues. | FirstGlance automatically detects [[Protein crosslinks|covalent protein crosslinks of six types]], plus disulfide bonds. Tools are provided making it easy to examine each such crosslink in detail. If the PDB file has been processed by [[ConSurf/Index|ConSurf]], it is easy to see the levels of conservation of the crosslinked residues. | ||
An example is isopeptide bond-linked chains of ubiquitin. [[7cap]] is an isopeptide-linked trimer of ubiquitin. Here is one ConSurf result: | An example is isopeptide bond-linked chains of ubiquitin. [[7cap]] is an isopeptide-linked trimer of ubiquitin. Here is one ConSurf result (300 sequences in the MSA with an APD of 1.15): | ||
:[http://firstglance.jmol.org/fg.htm?mol=7cap_consurf1639680092_pipe.pdb 7CAP Conservation in FirstGlance 3.8beta2] | :[http://firstglance.jmol.org/fg.htm?mol=7cap_consurf1639680092_pipe.pdb 7CAP Conservation in FirstGlance 3.8beta2] | ||
[[ | Here are [[Evaluating_Protein_Crosslinks#Instructions_for_an_Isopeptide_Bond|instructions for getting a list of the isopeptide bonds]]. | ||
==See Also== | ==See Also== | ||
