Sandbox Reserved 1645: Difference between revisions

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'''Fibrillin-1''' is a protein that is encoded in human bodies by the gene FBN1 situated on chromosome 15. Fibrillin-1 is a single protein chain of 230kb involving 65 exons from the class of '''[https://en.wikipedia.org/wiki/Glycoprotein glycoproteins]''' with a mass of 350kDa. The protein forms microfibrils located in the extracellular matrix, and thus has a role in the structural support of cells in elastic and nonelastic connective tissues in the human body. <ref>Handford, P. A. (2000). Fibrillin-1, a calcium binding protein of extracellular matrix. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1498(2), 84–90. https://doi.org/10.1016/S0167-4889(00)00085-9</ref>

Several other fibrillin protein exist such as Fibrillin 2, that plays a role in early elastogenesis. Fibrillin 3 is thought to be located mainly in the brain. Fibrillin 4 ~~have~~ a sequence similar to Fibrillin 2.

Several other fibrillin protein exist such as Fibrillin 2, that plays a role in early elastogenesis. Fibrillin 3 is thought to be located mainly in the brain. Fibrillin 4 has a sequence similar to Fibrillin 2.

Sandbox Reserved 1645: Difference between revisions

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Revision as of 14:45, 9 January 2022 view source Chloe Gutter (talk \| contribs) 17 edits No edit summary ← Older edit		Revision as of 14:45, 9 January 2022 view source Chloe Gutter (talk \| contribs) 17 edits No edit summary Newer edit →
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	'''Fibrillin-1''' is a protein that is encoded in human bodies by the gene FBN1 situated on chromosome 15. Fibrillin-1 is a single protein chain of 230kb involving 65 exons from the class of '''[https://en.wikipedia.org/wiki/Glycoprotein glycoproteins]''' with a mass of 350kDa. The protein forms microfibrils located in the extracellular matrix, and thus has a role in the structural support of cells in elastic and nonelastic connective tissues in the human body. <ref>Handford, P. A. (2000). Fibrillin-1, a calcium binding protein of extracellular matrix. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1498(2), 84–90. https://doi.org/10.1016/S0167-4889(00)00085-9</ref>		'''Fibrillin-1''' is a protein that is encoded in human bodies by the gene FBN1 situated on chromosome 15. Fibrillin-1 is a single protein chain of 230kb involving 65 exons from the class of '''[https://en.wikipedia.org/wiki/Glycoprotein glycoproteins]''' with a mass of 350kDa. The protein forms microfibrils located in the extracellular matrix, and thus has a role in the structural support of cells in elastic and nonelastic connective tissues in the human body. <ref>Handford, P. A. (2000). Fibrillin-1, a calcium binding protein of extracellular matrix. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1498(2), 84–90. https://doi.org/10.1016/S0167-4889(00)00085-9</ref>

	Several other fibrillin protein exist such as Fibrillin 2, that plays a role in early elastogenesis. Fibrillin 3 is thought to be located mainly in the brain. Fibrillin 4 ~~have~~ a sequence similar to Fibrillin 2.		Several other fibrillin protein exist such as Fibrillin 2, that plays a role in early elastogenesis. Fibrillin 3 is thought to be located mainly in the brain. Fibrillin 4 has a sequence similar to Fibrillin 2.