7qel: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 7qel is ~~ON HOLD until Paper Publication~~

==Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH011247==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[7qel]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QEL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QEL FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AUS:(2~{R})-~{N}-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)spiro[2.3]hexane-2-carboxamide'>AUS</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qel OCA], [https://pdbe.org/7qel PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qel RCSB], [https://www.ebi.ac.uk/pdbsum/7qel PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qel ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/OGG1_MOUSE OGG1_MOUSE] DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Mus musculus]]

[[Category: Davies JR]]

[[Category: Scaletti ER]]

[[Category: Stenmark P]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7qel is ON HOLD  until Paper Publication
+==Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH011247==
+<StructureSection load='7qel' size='340' side='right'caption='[[7qel]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7qel]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QEL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QEL FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AUS:(2~{R})-~{N}-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)spiro[2.3]hexane-2-carboxamide'>AUS</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qel OCA], [https://pdbe.org/7qel PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qel RCSB], [https://www.ebi.ac.uk/pdbsum/7qel PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qel ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/OGG1_MOUSE OGG1_MOUSE] DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Mus musculus]]
+[[Category: Davies JR]]
+[[Category: Scaletti ER]]
+[[Category: Stenmark P]]