2j9i: Difference between revisions
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<SX load='2j9i' size='340' side='right' viewer='molstar' caption='[[2j9i]], [[Resolution|resolution]] 17.00Å' scene=''> | <SX load='2j9i' size='340' side='right' viewer='molstar' caption='[[2j9i]], [[Resolution|resolution]] 17.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2j9i]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2j9i]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J9I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J9I FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j9i OCA], [https://pdbe.org/2j9i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j9i RCSB], [https://www.ebi.ac.uk/pdbsum/2j9i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j9i ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 17Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j9i OCA], [https://pdbe.org/2j9i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j9i RCSB], [https://www.ebi.ac.uk/pdbsum/2j9i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j9i ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/LGSN_MOUSE LGSN_MOUSE] May act as a component of the cytoskeleton or as a chaperone for the reorganization of intermediate filament proteins during terminal differentiation in the lens. Does not seem to have enzymatic activity.<ref>PMID:18178558</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</SX> | </SX> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Bateman | [[Category: Bateman OA]] | ||
[[Category: Orlova | [[Category: Orlova EV]] | ||
[[Category: Slingsby | [[Category: Slingsby C]] | ||
[[Category: Wang | [[Category: Wang L]] | ||
[[Category: White | [[Category: White HE]] | ||
[[Category: Wistow | [[Category: Wistow G]] | ||
[[Category: Wyatt | [[Category: Wyatt K]] | ||
Latest revision as of 09:35, 9 May 2024
Lengsin is a survivor of an ancient family of class I glutamine synthetases in eukaryotes that has undergone evolutionary re- engineering for a tissue-specific role in the vertebrate eye lens.
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