Sandbox Reserved 1653: Difference between revisions
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Piezo1 is a protein discovered recently. Therefore, its potential in medicine is in constant evolution. | Piezo1 is a protein discovered recently. Therefore, its potential in medicine is in constant evolution. | ||
Piezo1 can be used as diagnostic [https://en.wikipedia.org/wiki/Biomarker biomarkers] because it detects different mechanical forces and triggers a specific response adapted to the changes in the environment. For instance, it is sensitive to shear stress which has a major role in [https://en.wikipedia.org/wiki/Cardiovascular_physiology cardiovascular physiology]. | Piezo1 can be used as diagnostic [https://en.wikipedia.org/wiki/Biomarker biomarkers] because it detects different mechanical forces and triggers a specific response adapted to the changes in the environment. For instance, it is sensitive to shear stress which has a major role in [https://en.wikipedia.org/wiki/Cardiovascular_physiology cardiovascular physiology]. | ||
This mechanosensitive receptor is a candidate for therapeutic innovation more specifically in the case of cardiovascular and neurodegenerative diseases. | This mechanosensitive receptor is a candidate for therapeutic innovation more specifically in the case of cardiovascular and neurodegenerative diseases. | ||
These new therapies could be based on Piezo1 pharmacological modulators. Recently, several modulators have been found. | These new therapies could be based on Piezo1 pharmacological modulators. Recently, several modulators have been found. | ||
