Sandbox Reserved 1653: Difference between revisions

Revision as of 15:42, 15 January 2022 view source Camille Goblet (talk \| contribs) 23 edits No edit summary ← Older edit		Revision as of 15:43, 15 January 2022 view source Camille Goblet (talk \| contribs) 23 edits No edit summary Newer edit →
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	The structure of Piezo1 offers a plausible explanation for the origin of its tension [https://en.wikipedia.org/wiki/Gating_(electrophysiology) gating]. Indeed, if the semi-spherical dome becomes flatter when Piezo1 opens, then the channel membrane system will expand thanks to the flexibility of the blades.		The structure of Piezo1 offers a plausible explanation for the origin of its tension [https://en.wikipedia.org/wiki/Gating_(electrophysiology) gating]. Indeed, if the semi-spherical dome becomes flatter when Piezo1 opens, then the channel membrane system will expand thanks to the flexibility of the blades.
	However, because flattening does not constrain the pore to open wide, expansion and pore diameter are decoupled, such that Piezo1 can exhibit its small conductance and cation selectivity, properties that are essential to its function.<ref name ="Piezo Senses Tension"/>,<ref name="Lin" />		However, because flattening does not constrain the pore to open wide, expansion and pore diameter are decoupled, such that Piezo1 can exhibit its small conductance and cation selectivity, properties that are essential to its function.<ref name ="Piezo Senses Tension"/>,<ref name="Lin" />

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