Sandbox Reserved 1653: Difference between revisions
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== Relevance == | == Relevance == | ||
A majority of Piezo1’s structure has been resolved by [https://en.wikipedia.org/wiki/Cryogenic_electron_microscopy cryo-em] but still information is lacking on the N-term domain and some subregions. There is no full structure available yet which can be troublesome to understand the mechanism of the protein. Moreover, Piezo1 is present in a large number of tissues, but the differences in its roles are unclear. Further research is required to allow a better understanding of diseases linked to Piezo1 (like DHS), and thus a better treatment of those diseases. | |||
[http://www.rcsb.org/structure/5Z10 PBD] | [http://www.rcsb.org/structure/5Z10 PBD] | ||