Sandbox Reserved 1645: Difference between revisions
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== Biological Function == | == Biological Function == | ||
Fibrillin-1 is a ubiquitous protein mostly expressed in muscles in its monomeric form. The monomers then polymerize to form the 10 to 12nm of diameter '''microfibrils'''. In the microfibrils the fibrillin-1 is associated to various proteins such as MAGP-1, MAGP-2, fibulin 2 and fibulin 5, [https://www.omim.org/entry/130160 elastin], | Fibrillin-1 is a ubiquitous protein mostly expressed in muscles in its monomeric form. The monomers then polymerize to form the 10 to 12nm of diameter '''microfibrils'''. In the microfibrils the fibrillin-1 is associated to various proteins such as MAGP-1, MAGP-2, [https://www.omim.org/entry/135821?search=fibulin%202&highlight=2%20fibulin fibulin 2] and [https://www.omim.org/entry/604580?search=fibulin%205&highlight=5%20fibulin fibulin 5], [https://www.omim.org/entry/130160 elastin], [https://www.omim.org/entry/118661?search=versican&highlight=versican versican] and [https://www.omim.org/entry/150390?search=ltbp%201&highlight=1%20ltbp LTBP-1]. Those microfibrils constitute the elastic and non-elastic human connective tissues such as the dermis or the organs. | ||
Role in the [https://en.wikipedia.org/wiki/Cytokine cytokine] and '''growth factor regulation''': | Role in the [https://en.wikipedia.org/wiki/Cytokine cytokine] and '''growth factor regulation''': | ||
