Sandbox Reserved 1656: Difference between revisions
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[[Image:DUBspathways.PNG |thumb|center|Figure 1 : Role of DUBs in the ubiquitin pathways]] | [[Image:DUBspathways.PNG |thumb|center|Figure 1 : Role of DUBs in the ubiquitin pathways]] | ||
Some other deubiquitinating enzymes also have biological functions. The latter are for instance involved in growth control, transcription silencing, regulation and viral infection or even the processing of ubiquitin-like-modifications. | Some other deubiquitinating enzymes also have biological functions. The latter are for instance involved in growth control, transcription silencing, regulation and viral infection or even the processing of ubiquitin-like-modifications.<ref>DOI:https://doi.org/10.1080/10409239891204251</ref> | ||
== Disease == | == Disease == | ||
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==== Treatment ==== | ==== Treatment ==== | ||
DUBs are attractive targets for drug therapy. As a result, they may be used for it because they are widely involved in key regulatory processes. In fact, DUBs might function to regulate both stability and the activity of target proteins like oncogenes and tumor suppressors. | DUBs are attractive targets for drug therapy. As a result, they may be used for it because they are widely involved in key regulatory processes. In fact, DUBs might function to regulate both stability and the activity of target proteins like oncogenes and tumor suppressors.<ref>DOI:https://doi.org/10.1038/nrm2731</ref> | ||
</StructureSection> | </StructureSection> | ||
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== References == | == References == | ||
<references/> | <references/> | ||
