7tsx: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 7tsx is ~~ON HOLD until Paper Publication~~

==Structure of Enterobacter cloacae Cap2 bound to CdnD02 C-terminus, Apo state==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[7tsx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TSX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TSX FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tsx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tsx OCA], [https://pdbe.org/7tsx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tsx RCSB], [https://www.ebi.ac.uk/pdbsum/7tsx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tsx ProSAT]</span></td></tr>

[[Category: ~~Unreleased~~ Structures]]

</table>

== Function ==

[https://www.uniprot.org/uniprot/CDND2_ENTCL CDND2_ENTCL] CBASS (cyclic oligonucleotide-based antiphage signaling system) provides immunity against bacteriophage. The CD-NTase protein synthesizes cyclic nucleotides in response to infection; these serve as specific second messenger signals. The signals activate a diverse range of effectors, leading to bacterial cell death and thus abortive phage infection. A type II-C(AAG) CBASS system (PubMed:32839535).<ref>PMID:32544385</ref> <ref>PMID:32839535</ref> Cyclic trinucleotide synthase that catalyzes the synthesis of 3',3',3'-cyclic AMP-AMP-GMP as the major product, a second messenger for cell signal transduction.<ref>PMID:30787435</ref> Protects E.coli against phage T2 infection. When the cdnD-cap2-cap3-cap4 operon is introduced in E.coli there is a more than 10(3) decrease in the efficiency of T2 plaque formation. The operon does not protect against phage T5 and only about 10-fold against T7.<ref>PMID:32544385</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Enterobacter cloacae]]

[[Category: Large Structures]]

[[Category: Corbett KD]]

[[Category: Gu Y]]

[[Category: Lau RK]]

[[Category: Ledvina HE]]

[[Category: Quan Y]]

[[Category: Whiteley AT]]

[[Category: Ye Q]]

[[Category: Zhou H]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7tsx is ON HOLD  until Paper Publication
+==Structure of Enterobacter cloacae Cap2 bound to CdnD02 C-terminus, Apo state==
+<StructureSection load='7tsx' size='340' side='right'caption='[[7tsx]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7tsx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TSX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TSX FirstGlance]. <br>
-Description:
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tsx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tsx OCA], [https://pdbe.org/7tsx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tsx RCSB], [https://www.ebi.ac.uk/pdbsum/7tsx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tsx ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/CDND2_ENTCL CDND2_ENTCL] CBASS (cyclic oligonucleotide-based antiphage signaling system) provides immunity against bacteriophage. The CD-NTase protein synthesizes cyclic nucleotides in response to infection; these serve as specific second messenger signals. The signals activate a diverse range of effectors, leading to bacterial cell death and thus abortive phage infection. A type II-C(AAG) CBASS system (PubMed:32839535).<ref>PMID:32544385</ref> <ref>PMID:32839535</ref>   Cyclic trinucleotide synthase that catalyzes the synthesis of 3',3',3'-cyclic AMP-AMP-GMP as the major product, a second messenger for cell signal transduction.<ref>PMID:30787435</ref>   Protects E.coli against phage T2 infection. When the cdnD-cap2-cap3-cap4 operon is introduced in E.coli there is a more than 10(3) decrease in the efficiency of T2 plaque formation. The operon does not protect against phage T5 and only about 10-fold against T7.<ref>PMID:32544385</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Enterobacter cloacae]]
+[[Category: Large Structures]]
+[[Category: Corbett KD]]
+[[Category: Gu Y]]
+[[Category: Lau RK]]
+[[Category: Ledvina HE]]
+[[Category: Quan Y]]
+[[Category: Whiteley AT]]
+[[Category: Ye Q]]
+[[Category: Zhou H]]