2l5j: Difference between revisions

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==structure of the spliceosomal phosphopeptide P140 (phosphorylated form)==
==structure of the spliceosomal phosphopeptide P140 (phosphorylated form)==
<StructureSection load='2l5j' size='340' side='right'caption='[[2l5j]], [[NMR_Ensembles_of_Models | 8 NMR models]]' scene=''>
<StructureSection load='2l5j' size='340' side='right'caption='[[2l5j]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2l5j]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L5J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L5J FirstGlance]. <br>
<table><tr><td colspan='2'>[[2l5j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L5J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L5J FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2l5i|2l5i]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l5j OCA], [https://pdbe.org/2l5j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l5j RCSB], [https://www.ebi.ac.uk/pdbsum/2l5j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l5j ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l5j OCA], [https://pdbe.org/2l5j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l5j RCSB], [https://www.ebi.ac.uk/pdbsum/2l5j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l5j ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/RU17_HUMAN RU17_HUMAN]] Mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.  
[https://www.uniprot.org/uniprot/RU17_HUMAN RU17_HUMAN] Mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Briand, J]]
[[Category: Briand J]]
[[Category: Chaloin, O]]
[[Category: Chaloin O]]
[[Category: Cung, M]]
[[Category: Cung M]]
[[Category: Decossas, M]]
[[Category: Decossas M]]
[[Category: Dorsselaer, A van]]
[[Category: Muller S]]
[[Category: Muller, S]]
[[Category: Page N]]
[[Category: Page, N]]
[[Category: Quinternet M]]
[[Category: Quinternet, M]]
[[Category: Schall N]]
[[Category: Schall, N]]
[[Category: Strub J]]
[[Category: Strub, J]]
[[Category: Van Dorsselaer A]]
[[Category: Hsc70]]
[[Category: Lupus]]
[[Category: Phosphorylation]]
[[Category: Splicing]]