7r2m: Difference between revisions

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'''Unreleased structure'''


The entry 7r2m is ON HOLD
==SYNJ2BP complex with a synthetic Vangl2 peptide (9mer).==
 
<StructureSection load='7r2m' size='340' side='right'caption='[[7r2m]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
Authors: Carrasco, K., Cousido Siah, A., Gogl, G., Betzi, S., McEwen, A., Kostmann, C., Trave, G.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7r2m]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7R2M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7R2M FirstGlance]. <br>
Description: SYNJ2BP complex with a synthetic Vangl2 peptide (9mer).
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7r2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7r2m OCA], [https://pdbe.org/7r2m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7r2m RCSB], [https://www.ebi.ac.uk/pdbsum/7r2m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7r2m ProSAT]</span></td></tr>
[[Category: Kostmann, C]]
</table>
[[Category: Cousido Siah, A]]
== Function ==
[[Category: Betzi, S]]
[https://www.uniprot.org/uniprot/A0A4W2GEM6_BOBOX A0A4W2GEM6_BOBOX] Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.[ARBA:ARBA00003833][https://www.uniprot.org/uniprot/SYJ2B_HUMAN SYJ2B_HUMAN]
[[Category: Gogl, G]]
__TOC__
[[Category: Carrasco, K]]
</StructureSection>
[[Category: Trave, G]]
[[Category: Homo sapiens]]
[[Category: Mcewen, A]]
[[Category: Large Structures]]
[[Category: Betzi S]]
[[Category: Carrasco K]]
[[Category: Cousido Siah A]]
[[Category: Gogl G]]
[[Category: Kostmann C]]
[[Category: McEwen A]]
[[Category: Trave G]]
Retrieved from "https://proteopedia.org/7r2m"