7doj: Difference between revisions
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==Solution structure of TGS domain of the Mycobacterium tuberculosis Rel protein== | ==Solution structure of TGS domain of the Mycobacterium tuberculosis Rel protein== | ||
<StructureSection load='7doj' size='340' side='right'caption='[[7doj | <StructureSection load='7doj' size='340' side='right'caption='[[7doj]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7doj]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DOJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DOJ FirstGlance]. <br> | <table><tr><td colspan='2'>[[7doj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DOJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DOJ FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7doj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7doj OCA], [https://pdbe.org/7doj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7doj RCSB], [https://www.ebi.ac.uk/pdbsum/7doj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7doj ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7doj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7doj OCA], [https://pdbe.org/7doj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7doj RCSB], [https://www.ebi.ac.uk/pdbsum/7doj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7doj ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/RELA_MYCTU RELA_MYCTU] In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes both the formation of pppGpp, which is then hydrolyzed to form ppGpp, as well as the hydrolysis of ppGpp. RelA is probably a key factor in the pathogenesis of M.tuberculosis as it regulates the intracellular concentrations of (p)ppGpp.<ref>PMID:10375643</ref> <ref>PMID:10940033</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: | [[Category: Grueber G]] | ||
[[Category: | [[Category: Joon S]] | ||
[[Category: | [[Category: Singal B]] | ||
Latest revision as of 11:12, 14 June 2023
Solution structure of TGS domain of the Mycobacterium tuberculosis Rel protein
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