7vex: Difference between revisions
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<StructureSection load='7vex' size='340' side='right'caption='[[7vex]], [[Resolution|resolution]] 1.51Å' scene=''> | <StructureSection load='7vex' size='340' side='right'caption='[[7vex]], [[Resolution|resolution]] 1.51Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7vex]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VEX FirstGlance]. <br> | <table><tr><td colspan='2'>[[7vex]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VEX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VEX FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.51Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vex OCA], [https://pdbe.org/7vex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vex RCSB], [https://www.ebi.ac.uk/pdbsum/7vex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vex ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vex FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vex OCA], [https://pdbe.org/7vex PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vex RCSB], [https://www.ebi.ac.uk/pdbsum/7vex PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vex ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/TGTP2_MOUSE TGTP2_MOUSE] Involved in innate cell-autonomous resistance to intracellular pathogens, such as Toxoplasma gondii. During avirulent type II T. gondii infection, recruited to the parasitophorous vacuole (PV) membrane, leading to PV vesiculation and rupture, and subsequent digestion of the parasite within the cytosol (PubMed:19265156, PubMed:24563254). Not recruited to virulent type I T. gondii PV membrane (PubMed:19265156). May confer an antiviral state for vesicular stomatitis virus (PubMed:9725230).<ref>PMID:19265156</ref> <ref>PMID:24563254</ref> <ref>PMID:9725230</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Nitta | [[Category: Mus musculus]] | ||
[[Category: Saijo-Hamano | [[Category: Nitta R]] | ||
[[Category: Sakai | [[Category: Saijo-Hamano Y]] | ||
[[Category: Sakai N]] | |||
Latest revision as of 17:24, 29 November 2023
Crystal Structure of GTP-bound Irgb6
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