3fut: Difference between revisions

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<StructureSection load='3fut' size='340' side='right'caption='[[3fut]], [[Resolution|resolution]] 1.52&Aring;' scene=''>
<StructureSection load='3fut' size='340' side='right'caption='[[3fut]], [[Resolution|resolution]] 1.52&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3fut]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FUT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FUT FirstGlance]. <br>
<table><tr><td colspan='2'>[[3fut]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FUT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FUT FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.52&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3fuu|3fuu]], [[3fuv|3fuv]], [[3fuw|3fuw]], [[3fux|3fux]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ksgA, TTHA0083 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fut OCA], [https://pdbe.org/3fut PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fut RCSB], [https://www.ebi.ac.uk/pdbsum/3fut PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fut ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fut FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fut OCA], [https://pdbe.org/3fut PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fut RCSB], [https://www.ebi.ac.uk/pdbsum/3fut PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fut ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/RSMA_THET8 RSMA_THET8]] Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.[HAMAP-Rule:MF_00607]  
[https://www.uniprot.org/uniprot/RSMA_THET8 RSMA_THET8] Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.[HAMAP-Rule:MF_00607]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fu/3fut_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fu/3fut_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Thet8]]
[[Category: Thermus thermophilus HB8]]
[[Category: Belardinelli, R]]
[[Category: Belardinelli R]]
[[Category: Dahlberg, A E]]
[[Category: Dahlberg AE]]
[[Category: Demirci, H]]
[[Category: Demirci H]]
[[Category: Gregory, S T]]
[[Category: Gregory ST]]
[[Category: Gualerzi, C]]
[[Category: Gualerzi C]]
[[Category: Jogl, G]]
[[Category: Jogl G]]
[[Category: Seri, E]]
[[Category: Seri E]]
[[Category: 16s rrna methyltransferase]]
[[Category: Antibiotic resistance]]
[[Category: Dimethyltransferase]]
[[Category: Dual-specific methyltransferase]]
[[Category: Methyltransferase]]
[[Category: Rna-binding]]
[[Category: Rrna processing]]
[[Category: S-adenosyl-l-methionine]]
[[Category: Transferase]]
[[Category: Translation]]
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