1gl6: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
Line 1: Line 1:
[[Image:1gl6.jpg|left|200px]]
{{Seed}}
[[Image:1gl6.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1gl6|  PDB=1gl6  |  SCENE=  }}  
{{STRUCTURE_1gl6|  PDB=1gl6  |  SCENE=  }}  


'''PLASMID COUPLING PROTEIN TRWB IN COMPLEX WITH THE NON-HYDROLYSABLE GTP ANALOGUE GDPNP'''
===PLASMID COUPLING PROTEIN TRWB IN COMPLEX WITH THE NON-HYDROLYSABLE GTP ANALOGUE GDPNP===




==Overview==
<!--
The transfer of DNA across membranes and between cells is a central biological process; however, its molecular mechanism remains unknown. In prokaryotes, trans-membrane passage by bacterial conjugation, is the main route for horizontal gene transfer. It is the means for rapid acquisition of new genetic information, including antibiotic resistance by pathogens. Trans-kingdom gene transfer from bacteria to plants or fungi and even bacterial sporulation are special cases of conjugation. An integral membrane DNA-binding protein, called TrwB in the Escherichia coli R388 conjugative system, is essential for the conjugation process. This large multimeric protein is responsible for recruiting the relaxosome DNA-protein complex, and participates in the transfer of a single DNA strand during cell mating. Here we report the three-dimensional structure of a soluble variant of TrwB. The molecule consists of two domains: a nucleotide-binding domain of alpha/beta topology, reminiscent of RecA and DNA ring helicases, and an all-alpha domain. Six equivalent protein monomers associate to form an almost spherical quaternary structure that is strikingly similar to F1-ATPase. A central channel, 20 A in width, traverses the hexamer.
The line below this paragraph, {{ABSTRACT_PUBMED_11214325}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11214325 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_11214325}}


==About this Structure==
==About this Structure==
Line 30: Line 34:
[[Category: Ring helicase]]
[[Category: Ring helicase]]
[[Category: Type iv secretion system]]
[[Category: Type iv secretion system]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 17:42:55 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 05:28:06 2008''

Revision as of 02:28, 1 July 2008

File:1gl6.png

Template:STRUCTURE 1gl6

PLASMID COUPLING PROTEIN TRWB IN COMPLEX WITH THE NON-HYDROLYSABLE GTP ANALOGUE GDPNP

Template:ABSTRACT PUBMED 11214325

About this Structure

1GL6 is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

The bacterial conjugation protein TrwB resembles ring helicases and F1-ATPase., Gomis-Ruth FX, Moncalian G, Perez-Luque R, Gonzalez A, Cabezon E, de la Cruz F, Coll M, Nature. 2001 Feb 1;409(6820):637-41. PMID:11214325

Page seeded by OCA on Tue Jul 1 05:28:06 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1gl6&oldid=602718"