7r2t: Difference between revisions
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==SYNJ2BP complex with a phosphorylated Vangl2 peptide at the P-1 position.== | |||
<StructureSection load='7r2t' size='340' side='right'caption='[[7r2t]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7r2t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7R2T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7R2T FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7r2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7r2t OCA], [https://pdbe.org/7r2t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7r2t RCSB], [https://www.ebi.ac.uk/pdbsum/7r2t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7r2t ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Carrasco | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/A0A4W2GEM6_BOBOX A0A4W2GEM6_BOBOX] Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.[ARBA:ARBA00003833][https://www.uniprot.org/uniprot/SYJ2B_HUMAN SYJ2B_HUMAN] | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Betzi S]] | |||
[[Category: Carrasco K]] | |||
[[Category: Cousido Siah A]] | |||
[[Category: Gogl G]] | |||
[[Category: Kostmann C]] | |||
[[Category: McEwen A]] | |||
[[Category: Trave G]] | |||
Revision as of 06:55, 18 May 2023
SYNJ2BP complex with a phosphorylated Vangl2 peptide at the P-1 position.
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