7x89: Difference between revisions
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==Tid1== | |||
<StructureSection load='7x89' size='340' side='right'caption='[[7x89]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7x89]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7X89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7X89 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7x89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7x89 OCA], [https://pdbe.org/7x89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7x89 RCSB], [https://www.ebi.ac.uk/pdbsum/7x89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7x89 ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/DNJA3_HUMAN DNJA3_HUMAN] Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity. Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway. | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Jang J]] | ||
[[Category: Ryu | [[Category: Jo KS]] | ||
[[Category: | [[Category: Kang DH]] | ||
[[Category: | [[Category: Kim EH]] | ||
[[Category: | [[Category: Kim JH]] | ||
[[Category: Lee JH]] | |||
[[Category: Lee SH]] | |||
[[Category: Ryu H]] | |||
[[Category: Ryu KS]] | |||
[[Category: Sim DW]] | |||
[[Category: Won HS]] | |||
