7cvt: Difference between revisions
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==== | ==Crystal structure of the C85A/L194A/H234C mutant CLC-ec1 with Fab fragment== | ||
<StructureSection load='7cvt' size='340' side='right'caption='[[7cvt]]' scene=''> | <StructureSection load='7cvt' size='340' side='right'caption='[[7cvt]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7cvt]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_MS_198-1 Escherichia coli MS 198-1] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CVT FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cvt OCA], [https://pdbe.org/7cvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cvt RCSB], [https://www.ebi.ac.uk/pdbsum/7cvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cvt ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cvt OCA], [https://pdbe.org/7cvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cvt RCSB], [https://www.ebi.ac.uk/pdbsum/7cvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cvt ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CLCA_ECOLI CLCA_ECOLI] Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.<ref>PMID:12384697</ref> <ref>PMID:14985752</ref> <ref>PMID:16341087</ref> <ref>PMID:16905147</ref> <ref>PMID:18678918</ref> | |||
==See Also== | |||
*[[Antibody 3D structures|Antibody 3D structures]] | |||
*[[Ion channels 3D structures|Ion channels 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli MS 198-1]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Lim H-H]] | |||
[[Category: Mersch K]] | |||
[[Category: Park K]] | |||
[[Category: Robertson J]] | |||
Revision as of 16:17, 29 November 2023
Crystal structure of the C85A/L194A/H234C mutant CLC-ec1 with Fab fragment
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