7u9j: Difference between revisions
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==Crystal structure of Mesothelin-207 fragment== | |||
<StructureSection load='7u9j' size='340' side='right'caption='[[7u9j]], [[Resolution|resolution]] 2.09Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7u9j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7U9J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7U9J FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7u9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7u9j OCA], [https://pdbe.org/7u9j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7u9j RCSB], [https://www.ebi.ac.uk/pdbsum/7u9j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7u9j ProSAT]</span></td></tr> | ||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/MSLN_HUMAN MSLN_HUMAN] Antibodies against MSLN are detected in patients with mesothelioma and ovarian cancer. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MSLN_HUMAN MSLN_HUMAN] Membrane-anchored forms may play a role in cellular adhesion.<ref>PMID:8288629</ref> <ref>PMID:14676194</ref> Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.<ref>PMID:8288629</ref> <ref>PMID:14676194</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Esser L]] | |||
[[Category: Lin D]] | |||
[[Category: Tang WK]] | |||
[[Category: Xia D]] | |||
[[Category: Zhan J]] | |||
Revision as of 11:15, 1 February 2023
Crystal structure of Mesothelin-207 fragment
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