7yyj: Difference between revisions

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'''Unreleased structure'''


The entry 7yyj is ON HOLD  until Paper Publication
==Tetragonal crystal structure of YTHDF1 YTH domain (544AVV546 mutant)==
 
<StructureSection load='7yyj' size='340' side='right'caption='[[7yyj]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
Authors: Dalle Vedove, A., Cazzanelli, G., Lolli, G.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7yyj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YYJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YYJ FirstGlance]. <br>
Description: Tetragonal crystal structure of YTHDF1 YTH domain (544AVV546 mutant)
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yyj OCA], [https://pdbe.org/7yyj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yyj RCSB], [https://www.ebi.ac.uk/pdbsum/7yyj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yyj ProSAT]</span></td></tr>
[[Category: Dalle Vedove, A]]
</table>
[[Category: Lolli, G]]
== Function ==
[[Category: Cazzanelli, G]]
[https://www.uniprot.org/uniprot/YTHD1_HUMAN YTHD1_HUMAN] Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability.<ref>PMID:24284625</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Cazzanelli G]]
[[Category: Dalle Vedove A]]
[[Category: Lolli G]]

Revision as of 06:00, 2 March 2023

Tetragonal crystal structure of YTHDF1 YTH domain (544AVV546 mutant)

7yyj, resolution 2.10Å

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