Sandbox Reserved 1725: Difference between revisions

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==Vitamin K Epoxide Reductase==
==Vitamin K Epoxide Reductase==
<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='Test_Scene'>
<StructureSection load='' size='340' side='right' caption='Caption for this structure' scene='Test_Scene'>
This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.


== Introduction ==
== Introduction ==
Vitamin K epoxide reductase (VKOR) is the enzyme responsible for regenerating vitamin K from vitamin K epoxide to support blood coagulation.


=== Vitamin K Cycle ===
=== Vitamin K Cycle ===
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===Tyrosine 138 and Asparagine 80===
=== Catalytic Amino Acids ===
===Hydrophobic Interactions===
 
 
 
=== Hydrophobic Interactions ===


== Medical Relevance ==
== Medical Relevance ==
===Warfarin===
===Warfarin===
Warfarin is a structural mimic of Vitamin K that is used clinically as an anticoagulant.   
Warfarin is a structural mimic of Vitamin K that is used clinically as an anticoagulant.   
===Superwarfarins===
===Superwarfarins===


This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
 


</StructureSection>
</StructureSection>