Sandbox Reserved 1725: Difference between revisions
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=== Structural Overview === | === Structural Overview === | ||
VKOR consists of four <scene name='90/904330/Transmembrane_helices/1'>transmembrane helices</scene> embedded in the endoplasmic reticulum membrane. The files on the RCSB Protein Data Bank include a barrel domain that is not pertinent to the function of VKOR. The images presented here have been edited to remove the barrel domain and renumbered to correspond with the article by Liu. <ref name="Liu">PMID:33154105</ref>. The original image with the barrel domain in context is shown in Figure 2. Helices one and two are connected by the beta hairpin region which contains two of the active cysteines, C43 and C51. VKOR also has a cap domain covering the active site, made up of an anchor, loop, and helix. | VKOR consists of four <scene name='90/904330/Transmembrane_helices/1'>transmembrane helices</scene> embedded in the endoplasmic reticulum membrane. The files on the RCSB Protein Data Bank include a barrel domain that is not pertinent to the function of VKOR. The images presented here have been edited to remove the barrel domain and renumbered to correspond with the article by Liu. <ref name="Liu">PMID:33154105</ref>. The original image with the barrel domain in context is shown in Figure 2. Helices one and two are connected by the <scene name='90/904330/Betahairpin/1'>beta hairpin</scene> region which contains two of the active cysteines, C43 and C51. VKOR also has a cap domain covering the active site, made up of an anchor, loop, and helix. | ||
== Catalytic Cycle == | == Catalytic Cycle == | ||