Sandbox Reserved 1716: Difference between revisions
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==Significant Cysteines== | ==Significant Cysteines== | ||
<scene name='90/ | <scene name='90/904321/Cys52disulfidecys55/3'>Disulfide Bond Cysteine52-Cysteine55 TrVKORL</scene> | ||
==Vitamin K Epoxide== | ==Vitamin K Epoxide== | ||
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As mentioned above, Vitamin K epoxide is a part of the Vitamin K cycle, necessary for blood coagulation. In the cycle, Vitamin K epoxide reductase (VKOR) reduces Vitamin K epoxide to quinone, or the active form of Vitamin K. What is occurring is VKOR donated electrons to Vitamin K epoxide, and those electrons come from the S-H of one of the cysteine pairs discussed above. The one cysteine pair has to be reduced for the transfer of electrons to the substrate can occur. | As mentioned above, Vitamin K epoxide is a part of the Vitamin K cycle, necessary for blood coagulation. In the cycle, Vitamin K epoxide reductase (VKOR) reduces Vitamin K epoxide to quinone, or the active form of Vitamin K. What is occurring is VKOR donated electrons to Vitamin K epoxide, and those electrons come from the S-H of one of the cysteine pairs discussed above. The one cysteine pair has to be reduced for the transfer of electrons to the substrate can occur. | ||