Sandbox Reserved 1715: Difference between revisions
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==== Domains ==== | ==== Domains ==== | ||
'''VFT''': The extracellular location in which the two glutamate agonists bind is known as the VFT. This domain includes a disulfide bond which is shifted down in the inactive form (IMAGE) and undergoes an upward movement upon glutamate binding which stabilizes the active site. | [[Image: Active vs inactive vft.png|400 px|left|thumb|Figure 1. The interaction between an active mGlu and a G-protein ]]'''VFT''': The extracellular location in which the two glutamate agonists bind is known as the VFT. This domain includes a disulfide bond which is shifted down in the inactive form (IMAGE) and undergoes an upward movement upon glutamate binding which stabilizes the active site. | ||