Sandbox Reserved 1709: Difference between revisions
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=== Brief Overview === | === Brief Overview === | ||
The <scene name='90/906893/Open_conformation/1'>open conformation</scene> will be prepped and waiting for a substrate or ligand to bind. Once the substrate binds, this will induce the | The <scene name='90/906893/Open_conformation/1'>open conformation</scene> will be prepped and waiting for a substrate or ligand to bind. Once the substrate binds, this will induce the <scene name='90/904314/Closed_conformation/1'>Closed conformation</scene> of VKOR, where the catalytic mechanism will activate Vitamin K via reactive cysteine residues. Vitamin K will then be released from the binding pocket once it is fully activated for use in the body, and VKOR will resume the open conformation once again. The enzyme will then reset into its reactive state to prep for another molecule of Vitamin K to bind. | ||