2vom: Difference between revisions
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<StructureSection load='2vom' size='340' side='right'caption='[[2vom]], [[Resolution|resolution]] 1.85Å' scene=''> | <StructureSection load='2vom' size='340' side='right'caption='[[2vom]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2vom]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2vom]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VOM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VOM FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vom FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vom OCA], [https://pdbe.org/2vom PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vom RCSB], [https://www.ebi.ac.uk/pdbsum/2vom PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vom ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vom FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vom OCA], [https://pdbe.org/2vom PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vom RCSB], [https://www.ebi.ac.uk/pdbsum/2vom PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vom ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | |||
[https://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN] Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:[https://omim.org/entry/190450 190450]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN] | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Aguirre-Lopez B]] | |||
[[Category: Aguirre-Lopez | [[Category: Arreola-Alemon R]] | ||
[[Category: Arreola-Alemon | [[Category: Costas M]] | ||
[[Category: Costas | [[Category: Gomez-Puyou A]] | ||
[[Category: Gomez-Puyou | [[Category: Perez-Montfort R]] | ||
[[Category: Rodriguez-Almazan C]] | |||
[[Category: Perez-Montfort | [[Category: Rodriguez-Larrea D]] | ||
[[Category: Rodriguez-Almazan | [[Category: Torres-Larios A]] | ||
[[Category: Rodriguez-Larrea | [[Category: De Gomez-Puyou MT]] | ||
[[Category: Torres-Larios | |||
[[Category: | |||
