Neurofibromin: Difference between revisions
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GAPex | GAPex | ||
====SPRED-1 Protein==== | ====SPRED-1 Protein==== | ||
The SPRED-1 protein <scene name='90/904325/Nf1_ras_spred1/1'>localizes neurofibromin</scene> to the cell membrane in to allow it to bind to the membrane oriented Ras protein<ref name= ''Naschberger''>PMID:34707296</ref>. SPRED-1 interacts with the N-terminal domain of NF to guide it to the membrane from the cytosol, where its C terminal domain will determine its target <ref name= ''Dunzendorfer-Matt''>PMID:27313208</ref>. | The SPRED-1 protein <scene name='90/904325/Nf1_ras_spred1/1'>localizes neurofibromin</scene> to the cell membrane in to allow it to bind to the membrane oriented Ras protein<ref name= ''Naschberger''>PMID:34707296</ref>. <scene name='90/904325/Spred_1/1'>SPRED-1</scene> interacts with the N-terminal domain of NF to guide it to the membrane from the cytosol, where its C terminal domain will determine its target <ref name= ''Dunzendorfer-Matt''>PMID:27313208</ref>. | ||
====Ras binding site==== | ====Ras binding site==== | ||
