7u4q: Difference between revisions
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==Human Synaptotagmin-1 C2A Y181F Ca2+ bound== | |||
<StructureSection load='7u4q' size='340' side='right'caption='[[7u4q]], [[Resolution|resolution]] 1.56Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7u4q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7U4Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7U4Q FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7u4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7u4q OCA], [https://pdbe.org/7u4q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7u4q RCSB], [https://www.ebi.ac.uk/pdbsum/7u4q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7u4q ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Fuson | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/SYT1_HUMAN SYT1_HUMAN] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. | ||
[[Category: | __TOC__ | ||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Dominguez MJ]] | |||
[[Category: Fuson KL]] | |||
[[Category: Karmakar S]] | |||
[[Category: Sutton RB]] | |||
Revision as of 09:47, 15 March 2023
Human Synaptotagmin-1 C2A Y181F Ca2+ bound
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