3tpf: Difference between revisions

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<StructureSection load='3tpf' size='340' side='right'caption='[[3tpf]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='3tpf' size='340' side='right'caption='[[3tpf]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3tpf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Camje Camje]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TPF FirstGlance]. <br>
<table><tr><td colspan='2'>[[3tpf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_NCTC_11168_=_ATCC_700819 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TPF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1c9y|1c9y]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">argF, Cj0994c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=192222 CAMJE])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ornithine_carbamoyltransferase Ornithine carbamoyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.3 2.1.3.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tpf OCA], [https://pdbe.org/3tpf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tpf RCSB], [https://www.ebi.ac.uk/pdbsum/3tpf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tpf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tpf OCA], [https://pdbe.org/3tpf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tpf RCSB], [https://www.ebi.ac.uk/pdbsum/3tpf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tpf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/OTC_CAMJE OTC_CAMJE]] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline (By similarity).[HAMAP-Rule:MF_01109]
[https://www.uniprot.org/uniprot/OTCA_CAMJE OTCA_CAMJE] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase (ArgG) involved in the final step in arginine biosynthesis.<ref>PMID:22949186</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Camje]]
[[Category: Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ornithine carbamoyltransferase]]
[[Category: Anderson WF]]
[[Category: Anderson, W F]]
[[Category: Chruszcz M]]
[[Category: Structural genomic]]
[[Category: Grabowski M]]
[[Category: Chruszcz, M]]
[[Category: Grimshaw S]]
[[Category: Grabowski, M]]
[[Category: Minor W]]
[[Category: Grimshaw, S]]
[[Category: Onopriyenko O]]
[[Category: Minor, W]]
[[Category: Porebski PJ]]
[[Category: Onopriyenko, O]]
[[Category: Savchenko A]]
[[Category: Porebski, P J]]
[[Category: Shabalin IG]]
[[Category: Savchenko, A]]
[[Category: Shabalin, I G]]
[[Category: Carbamoyl phosphate binding]]
[[Category: Csgid]]
[[Category: L-ornithine binding]]
[[Category: Rossmann fold]]
[[Category: Transferase]]
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