3i6r: Difference between revisions

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<StructureSection load='3i6r' size='340' side='right'caption='[[3i6r]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3i6r' size='340' side='right'caption='[[3i6r]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3i6r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I6R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I6R FirstGlance]. <br>
<table><tr><td colspan='2'>[[3i6r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I6R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I6R FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=J5Z:5-METHYL-N-[4-(TRIFLUOROMETHYL)PHENYL][1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-AMINE'>J5Z</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3i65|3i65]], [[3i68|3i68]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=J5Z:5-METHYL-N-[4-(TRIFLUOROMETHYL)PHENYL][1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-AMINE'>J5Z</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PFF0160c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i6r OCA], [https://pdbe.org/3i6r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i6r RCSB], [https://www.ebi.ac.uk/pdbsum/3i6r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i6r ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i6r OCA], [https://pdbe.org/3i6r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i6r RCSB], [https://www.ebi.ac.uk/pdbsum/3i6r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i6r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PYRD_PLAF7 PYRD_PLAF7]] Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.  
[https://www.uniprot.org/uniprot/PYRD_PLAF7 PYRD_PLAF7] Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Plaf7]]
[[Category: Plasmodium falciparum 3D7]]
[[Category: Deng, X]]
[[Category: Deng X]]
[[Category: Phillips, M A]]
[[Category: Phillips MA]]
[[Category: Dihydroorotate dehydrogenase]]
[[Category: Dsm74]]
[[Category: Fad]]
[[Category: Flavoprotein]]
[[Category: Inhibitor]]
[[Category: Membrane]]
[[Category: Mitochondrion]]
[[Category: Mitochondrion inner membrane]]
[[Category: Oxidoreductase]]
[[Category: Plasmodium falciparum]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Transit peptide]]
[[Category: Triazolopyrimidine]]
Retrieved from "https://proteopedia.org/3i6r"