3i6x: Difference between revisions

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<StructureSection load='3i6x' size='340' side='right'caption='[[3i6x]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3i6x' size='340' side='right'caption='[[3i6x]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3i6x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I6X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I6X FirstGlance]. <br>
<table><tr><td colspan='2'>[[3i6x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I6X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I6X FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IQGAP1, KIAA0051 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i6x OCA], [https://pdbe.org/3i6x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i6x RCSB], [https://www.ebi.ac.uk/pdbsum/3i6x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i6x ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i6x OCA], [https://pdbe.org/3i6x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i6x RCSB], [https://www.ebi.ac.uk/pdbsum/3i6x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i6x ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/IQGA1_HUMAN IQGA1_HUMAN]] Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.<ref>PMID:15695813</ref>
[https://www.uniprot.org/uniprot/IQGA1_HUMAN IQGA1_HUMAN] Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.<ref>PMID:15695813</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Kurella, V B]]
[[Category: Kurella VB]]
[[Category: All helical]]
[[Category: Calmodulin-binding]]
[[Category: Cell membrane]]
[[Category: Membrane]]
[[Category: Membrane protein]]
[[Category: Phosphoprotein]]
[[Category: Protein binding]]
Retrieved from "https://proteopedia.org/3i6x"