Sandbox Reserved 1706: Difference between revisions
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==Ras Binding== | ==Ras Binding== | ||
Arg1276 is the critical residue within the GRD site for Ras activation. | Arg1276 is the critical residue within the GRD site for Ras activation. When <scene name='90/904311/Arg_1276_open/13'>Arg1276 is in the open conformation</scene> | ||
<jmol> | <jmol> | ||
<jmolButton> | <jmolButton> | ||
<script>moveto 1.0 { -776 433 -458 146.98} 7209.11 0.0 0.0 {361.5375833333334 402.0207083333333 360.750125} 190.41144084626742 {0 0 0} 0 0 0 3.0 0.0 0.0</script> <text>🔎</text> | <script>moveto 1.0 { -776 433 -458 146.98} 7209.11 0.0 0.0 {361.5375833333334 402.0207083333333 360.750125} 190.41144084626742 {0 0 0} 0 0 0 3.0 0.0 0.0</script> <text>🔎</text> | ||
</jmolButton> | </jmolButton> | ||
</jmol>, the arginine finger binds to the backbone γ-carbon of Y32 in Ras to assist in eventual hydrolysis of GTP. <scene name='90/904311/Closed_zoom/10'> | </jmol>, the arginine finger binds to the backbone γ-carbon of Y32 in Ras to assist in eventual hydrolysis of GTP. <scene name='90/904311/Closed_zoom/10'>Arg1276 in the closed conformation</scene> | ||
<jmol> | <jmol> | ||
<jmolButton> | <jmolButton> | ||
