7o6s: Difference between revisions
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==Crystal structure of a shortened IpgC variant in complex with N-(2H-1,3-benzodioxol-5-ylmethyl)cyclopentanamine== | ==Crystal structure of a shortened IpgC variant in complex with N-(2H-1,3-benzodioxol-5-ylmethyl)cyclopentanamine== | ||
<StructureSection load='7o6s' size='340' side='right'caption='[[7o6s]]' scene=''> | <StructureSection load='7o6s' size='340' side='right'caption='[[7o6s]], [[Resolution|resolution]] 1.58Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7O6S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7O6S FirstGlance]. <br> | <table><tr><td colspan='2'>[[7o6s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7O6S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7O6S FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7o6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7o6s OCA], [https://pdbe.org/7o6s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7o6s RCSB], [https://www.ebi.ac.uk/pdbsum/7o6s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7o6s ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=45N:N-(1,3-BENZODIOXOL-5-YLMETHYL)CYCLOPENTANAMINE'>45N</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7o6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7o6s OCA], [https://pdbe.org/7o6s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7o6s RCSB], [https://www.ebi.ac.uk/pdbsum/7o6s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7o6s ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/IPGC_SHIFL IPGC_SHIFL] Assists the correct folding of nascent IpaB. Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG. | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Shigella flexneri]] | |||
[[Category: Gardonyi M]] | [[Category: Gardonyi M]] | ||
[[Category: Heine A]] | [[Category: Heine A]] | ||
[[Category: Klebe G]] | [[Category: Klebe G]] | ||
Latest revision as of 12:45, 1 February 2024
Crystal structure of a shortened IpgC variant in complex with N-(2H-1,3-benzodioxol-5-ylmethyl)cyclopentanamine
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