7sbf: Difference between revisions
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==== | ==PZM21 bound Mu Opioid Receptor-Gi Protein Complex== | ||
<StructureSection load='7sbf' size='340' side='right'caption='[[7sbf]]' scene=''> | <StructureSection load='7sbf' size='340' side='right'caption='[[7sbf]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7sbf]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SBF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SBF FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sbf OCA], [https://pdbe.org/7sbf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sbf RCSB], [https://www.ebi.ac.uk/pdbsum/7sbf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sbf ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8QY:N-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-N-[(2S)-1-(thiophen-3-yl)propan-2-yl]urea'>8QY</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7sbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7sbf OCA], [https://pdbe.org/7sbf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7sbf RCSB], [https://www.ebi.ac.uk/pdbsum/7sbf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7sbf ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN]] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref> | |||
==See Also== | |||
*[[Transducin 3D structures|Transducin 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Huang W]] | |||
[[Category: Kobilka B]] | |||
[[Category: Qu Q]] | |||
[[Category: Skiniotis G]] | |||
[[Category: Wang H]] | |||
Revision as of 07:21, 8 September 2022
PZM21 bound Mu Opioid Receptor-Gi Protein Complex
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